The development of osteoarthritis is closely related to articular cartilage cells. Articular cartilage is a layer of tissue about 3-5mm thick that covers the bones. It is mainly composed of collagen fibers, and its role is to secrete synovial fluid to protect the joints. It is an indispensable “buffer zone” between the bones, which can buffer the vibration and impact on bone by external force thus protecting bones from being worn and decreasing the pressure on joints. No matter walking, running, or jumping, the presence of cartilage helps to reduce vibration and friction in our joints. But since cartilage does not contain any blood vessels, its self-repair ability is very low, and it is difficult to fully regenerate after injury, and injured cartilage may continuously develop into osteoarthritis.